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Tobacco-free nicotine products are suggested as a smoking cessation strategy in some countries, but as the nicotine product is still highly addictive, new addictions develop with local oral changes as a side effect [8]

Results Acquisition of active ingredients and target prediction of RD and LF We successfully identified key active components in RD and LF using the TCMSP

Centers for Disease Control and Prevention (CDC) has stated that sometimes e-cigarette products are changed or modified and can have possibly harmful or illegal substances from unknown sources

Surgery, chemotherapy, and radiation therapy (or any combination of these) may be performed, as well as neck dissection if regional lymph node metastasis is suspected