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Unpaired t -tests were applied to compare two groups, three or more groups were compared with a one-way ANOVA followed by Tukeys or Dunnetts multiple comparisons test, and two-factor analyses were conducted with a mixed-effects model followed by dks or Tukeys multiple comparisons test

After almost a decade of empirical research, the evidence is clear that higher taxes on safer nicotine products like e-cigarettes result in more smoking of traditional cigarettes