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Propylene glycol is a known skin irritant and contact sensitiser at high concentrations it is used in patch testing specifically because it can produce contact reactions in sensitive individuals

76017 dated 29-7/01-08-2002 Selling of tobacco products is prohibited to and from minors (3730/2008 Act, art

In addition, one serious concern is that nicotine is often found in the e-liquids, even if the label says 0 mg of nicotine

"We believe you have a continuing responsibility to take action to address the epidemic of youth use of your products, some of which appears to have been a direct result of your product design and marketing campaigns, whether or not some of these practices have been discontinued," the FDA wrote.