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Compared with the careers of users of illegal drugs, which peak in the 20s and then trail off by the mid-30s, careers of cigarette smokers follow a different trajectory

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A growing body of research suggests that the dysregulation of the nicotinic cholinergic system is responsible for modulating the sensory processing input processes, which accounts for the control issues that are typical of ADHD [73] nAChRs also have a role in the regulation of neurotransmitters including dopamine and serotonin