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United States Value: Percentage of adults who reported smoking at least 100 cigarettes in their lifetime and currently smoke daily or some days Percentage of adults who reported smoking at least 100 cigarettes in their lifetime and currently smoke daily or some days 5.7% - 9.1% 9.2% - 10.5% 10.6% - 12.2% 12.3% - 13.9% 14.0% - 20.8% No Data US Value: 11.6% Top State(s): Utah: 5.7% Bottom State(s): West Virginia: 20.8% Definition: Percentage of adults who reported smoking at least 100 cigarettes in their lifetime and currently smoke daily or some days Data Source and Years(s): U.S

[2] In response to the smoking, STAT3 and STAT6 signaling are stimulated to potentiate M2-like phenotype with elevated IL-6, IL-10, IL-12, and TGF-b