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According to the research team leader Prue Talbot, professor in the Department of Molecular, Cell and Systems Biology at the University of California, Riverside: We found some flavor chemicals, such as ethyl maltol, also correlate with cytotoxicity, but nicotine seems to be the most potent chemical in Juul products, due to it very high concentration. Although federal regulations limit the sales of Juul products to individuals 21 years and older, Juuling still remains prominent among adolescents, primarily middle-school and high-school-aged youth

Upper-lobe predominance of emphysema was also more common in combined smokers, seen in 55% of them versus 32% in tobacco-only smokers (Pradre et al., 2026)

Which makes them very appealing, maybe

Most of the samples of THC vape products also contained significant amounts of vitamin E acetate, according to the FDA