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The tobacco blend, the size, the filter tip, the package, the carton and the advertising, a Reynolds spokesman said, were all designed to appeal to the woman smoker. Packaging innovations with a special appeal to women include a package that is half-way between the normal soft pack and a flip-top box, a self-locking flap that closes over the cigarettes to keep loose tobacco from falling out in purses, and embossing that gives the entire package the feel of a fabric cigarette case

Michael Siegel, a professor at the Boston University School of Public Health and a career anti-smoking researcher, notes that this obsession with minor differences represents a curious role reversal, with cigarette companies now reminding regulators that "indeed all cigarettes are hazardous and there is no such thing as a safer cigarette." "My opinion is that most, if not all of the substantial equivalence applications involve minor changes that have no substantial bearing on altering the public health significance or impact of the products," says Siegel

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