Azide-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-PNP Size:100mg DOTA bifucational chelator containing an

DOTA bifucational chelator containing an alcohol group

RSC Medicinal Chemistry

SuO-Glu-Val-Cit-PAB-MMAE (NHS-Glutarate-Val-Cit-PAB-MMAE) is a cleavable ADC linker–payload system consisting of a SuO-Glu-Val-Cit-PAB peptide linker and the microtubule-disrupting cytotoxic payload MMAE

281 SMILES BrCCCCCC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Azide-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-PNP Size:100mg DOTA bifucational chelator containing anSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Azide Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The azide functional group is widely utilized in bioconjugation via click chemistry to enable efficient and selective attachment of biomolecules. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase