Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-Exatecan adc can be hydrolyzed by intracellular

can be hydrolyzed by intracellular esterases to release the fluorescent fluorescein core

Product Name Lenalidomide-CO-C3-amine HCl Synonyms Lenalidomide-4'-CO-C3-amine HCl CAS Number 2353563-41-2 Related CAS Molecular Formula C17H21ClN4O4 Molecular Weight 380

TAMRA (TMR)is a bright orange fluorophore

3-dione Synonyms 1-(²H3)methyl-2

Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-Exatecan adc can be hydrolyzed by intracellularSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is Exatecan,