Azide-Hexanoyl-Val-Cit-PAB(m-PEG8)-Exatecan cit Product Name Thalidomide-5'-piperidine-C1-piperazine HCl Synonyms

Product Name Thalidomide-5'-piperidine-C1-piperazine HCl Synonyms CAS Number n/a Related CAS Molecular Formula C23H31Cl2N5O4 Molecular Weight 512

S)-AHPC-CO-PEG5-C2-acid Synonyms CAS Number 2172820-14-1 Related CAS Molecular Formula C36H54N4O11S Molecular Weight 750

NBD-TM is a thiomorpholine-based fluorogenic probe for HOCl

Product Name 5-bromo-2-(methoxy-d3)pyridine Synonyms 5-bromo-2-(²H3)methoxypyridine CAS Number 1185319-63-4 Related CAS Molecular Formula C6H6BrNO Molecular Weight 191

Azide-Hexanoyl-Val-Cit-PAB(m-PEG8)-Exatecan cit Product Name Thalidomide-5'-piperidine-C1-piperazine HCl SynonymsSOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC