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DBCO-Hexanoyl-Val-Cit-PAB(m-PEG8)-MMAE Size:10mg 64 SMILES Cl

DBCO-Hexanoyl-Val-Cit-PAB(m-PEG8)-MMAE Size:10mg 64 SMILES ClSOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing

SKU: 26684388179 · From clintoncounty708.com

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Description

64 SMILES Cl

which recruit the VHL or CRBN-ubiquitin E3 ligases to induce the degradation of SNAP-fusion proteins

374 Purity (HPLC) >= 95% Solubility DMSO

Datasheet          MSDS

DBCO-Hexanoyl-Val-Cit-PAB(m-PEG8)-MMAE Size:10mg 64 SMILES ClSOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing

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