Fmoc-Val-Cit-PAB dsa 3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5

3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5

It promotes degradeation of phosphodiesterase 6D (PDE6D)

918 Purity (HPLC) >= 95% Solubility DMSO

Its active site binds chloroalkane (CA)substrates

Fmoc-Val-Cit-PAB dsa 3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5Fmoc Val Cit PAB is a cleavable ADC linker featuring a ValCit dipeptide and a para aminobenzyl (PAB) spacer. The ValCit sequence is selectively cleaved by cathepsin B in lysosomes, while the para aminobenzyl (PAB) spacer supports self immolative release of the attached drug, and the Fmoc protecting group can be removed to enable further functionalization or conjugation. Product Name Fmoc Val Cit PAB Synonyms Fmoc VC PAB OH CAS Number 159858 22 7