Mal-Propionyl-PEG2-Val-Cit-PAB(m-PEG4)-Exatecan ligand Product Name Mal-Propionyl-PEG2-Val-Cit-PAB(m-PEG4) Synonyms CAS

Product Name Mal-Propionyl-PEG2-Val-Cit-PAB(m-PEG4) Synonyms CAS Number Related CAS Molecular Formula C42H66N8O15 Molecular Weight 923

Product Name Lenalidomide-C5-OH Synonyms Lenalidomide-4'-C5-OH CAS Number n/a Related CAS Molecular Formula C18H23N3O4 Molecular Weight 345

The water soluble 5(6)-FAM PEG3 azide has a long PEG3 spacer that separates the dye carboxyfluorescein (commonly known as FAM) from the terminal azide group

438 Purity (HPLC) >= 95% Solubility DMSO

Mal-Propionyl-PEG2-Val-Cit-PAB(m-PEG4)-Exatecan ligand Product Name Mal-Propionyl-PEG2-Val-Cit-PAB(m-PEG4) Synonyms CASSOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I