NRX-103095 dacf1 69 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCOCCBr)C(C)(C)C)C=C1 Purity (HPLC)

69 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCOCCBr)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name DOTA-hexyne Synonyms CAS Number n/a Related CAS Molecular Formula C22H37N5O7 Molecular Weight 483

NCCOCCOCCOCC#CC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name auxin Synonyms indole-3-acetic acid CAS Number 87-51-4 Related CAS Molecular Formula C10H9NO2 Molecular Weight 175

NRX-103095 dacf1 69 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCOCCBr)C(C)(C)C)C=C1 Purity (HPLC)NRX 103095 is an enhancer of the interaction between beta catenin and beta TrCP. NRX 103095 acts as molecular glue in cells to promote the ubiquitylation and subsequent degradation of mutantbeta catenin by the 26S proteasome. Product Name NRX 103095 Synonyms CAS Number 2763260 38 2 Related CAS Molecular Formula C22H16Cl2F3N3O3S Molecular Weight 530. 34 SMILES CN(C)C(=O)C1=CC=CC(NC(=O)C2=C(SC3=C(Cl)C=CC=C3Cl)C=C(NC2=O)C(F)(F)F)=C1 Purity (HPLC) >= 95%