Mal-Propionyl-PEG6-Val-Cit-PAB(m-PEG4)-PNP pnp The water soluble 5(6)-TAMRA PEG3

The water soluble 5(6)-TAMRA PEG3 alkyne has a long PEG3 spacer that separates the dye tetramethylrhodamine (commonly known as TMR or TAMRA) from the terminal acetylene group

13 Purity (HPLC) >= 95% Solubility DMSO

692 Purity (HPLC) >= 95% Solubility DMSO

Product Name Azide-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C66H90FN13O20 Molecular Weight 1404

Mal-Propionyl-PEG6-Val-Cit-PAB(m-PEG4)-PNP pnp The water soluble 5(6)-TAMRA PEG3SOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG6 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating