Mal-Propionyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4) propargyl-acetyl Product Name: Cy3 azide trisulfo

Product Name: Cy3 azide trisulfo Synonyms: Cy3 azide

while the para-aminobenzyl (PAB) spacer supports self-immolative release of the attached drug

HQ461 is a molecular glue that promotes CDK12-DDB1 interaction to trigger cyclin K degradation

78 SMILES ClCCOCC(=O)NC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Mal-Propionyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4) propargyl-acetyl Product Name: Cy3 azide trisulfoSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Propionyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. Derived from