Azide-Dap(m-PEG4)-Val-Cit-PAB 5' Product Name Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4)-PNP Synonyms CAS

Product Name Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4)-PNP Synonyms CAS Number Related CAS Molecular Formula C54H79N11O21 Molecular Weight 1218

Product Name Thalidomide-O-PEG1-C2-Br Synonyms Thalidomide-4'-O-PEG1-C2-Br CAS Number n/a Related CAS Molecular Formula C17H17BrN2O6 Molecular Weight 425

Product Name Fmoc-Val-Cit-PAB(m-PEG8)-PNP Synonyms CAS Number Related CAS Molecular Formula C58H77N7O19 Molecular Weight 1176

Linker substitution influences succinimide ring hydrolysis equilibrium impacting the stability of attachment to antibody-drug conjugates

Azide-Dap(m-PEG4)-Val-Cit-PAB 5' Product Name Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4)-PNP Synonyms CASSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Azide Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The azide functional group is widely utilized in bioconjugation via click chemistry to enable efficient and selective attachment of biomolecules. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine