Mal-Propionyl-PEG8-Val-Cit-PAB(m-PEG4)-Exatecan deuterium-labeled-ether 438 SMILES OCCCCCCCC1=CC=C2C(=O)N(CC2=C1)C1CCC(=O)NC1=O Purity (HPLC)

438 SMILES OCCCCCCCC1=CC=C2C(=O)N(CC2=C1)C1CCC(=O)NC1=O Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Development of a Fluorescent Probe for M2 Macrophages via Gating-Oriented Live-Cell Distinction

Product Name BG-SulfoCy3 Synonyms SNAP-SulfoCy3 CAS Number Related CAS Molecular Formula C43H48N8O8S2 Molecular Weight 869

Product Name tert-butyl 2-[4-(2-aminoethyl)piperazin-1-yl]acetate Synonyms CAS Number n/a Related CAS Molecular Formula C12H25N3O2 Molecular Weight 243

Mal-Propionyl-PEG8-Val-Cit-PAB(m-PEG4)-Exatecan deuterium-labeled-ether 438 SMILES OCCCCCCCC1=CC=C2C(=O)N(CC2=C1)C1CCC(=O)NC1=O Purity (HPLC)SOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG8 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I