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Disturbing indifference to the vast illegal market for ENDS The FDAs Draft Guidance is strongly at odds with reality regarding the illegal market that dominates ENDS use in the United States, which likely accounts for at least 80% of the total ENDS market when tracked and untracked sales are considered (see Figure 5 below)

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Statistical analysis As a principal summary measure, pooled odds ratios (ORs) and 95% confidence intervals (CIs) were calculated from each study

His father (also a Navy veteran) died while he was serving his country