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The multicentre, randomized, double-blind, placebo-controlled ALADIN III trial demonstrated significant improvement in the Neuropathy Impairment Score (NIS) in patients who received -lipoic acid but no significant improvement in the Total Symptom Score (TSS) 176

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[32] Ashizawa, Tatsuto, et al

Their molecular information, chromosomal locations, phylogenetic relationships, synteny relationships, gene structures, proteinprotein interactions, structure of 3-D models, and expression levels under cold stress were analyzed