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While nicotine is the addictive substance in cigarettes, most of the harm from smoking comes from the thousands of other chemicals in tobacco smoke, many of which are toxic

"Additionally, the proposed rules represent an important step to advance health equity by significantly reducing tobacco-related health disparities." E-CIGS USING SYNTHETIC NICOTINE NOW UNDER FDA OVERSIGHT The rules, the FDA said, build on the Family Smoking Prevention and Tobacco Control Act and are also a critical component of the Biden administration's Cancer Moonshot

INTRODUCTION Smoking is a major public health issue, as it is a leading cause of preventable death and disease worldwide, contributing to more than 8 million deaths each year 1

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