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SARS-Cov-2 virus infection may initiate a strong inflammatory and dysregulated reaction in the lung with increased levels of IL-6 and a cytokine-storm (129) which has been shown to provoke either an asymptomatic, mild, or severe infections This cytokine dysregulation may be associated with neutrophil extracellular traps (130) and alterations in T cell activity (131)

When stimuli are applied, smart drug carriers encounter phase transitions and conformational changes that release bioactive components in a site-specific, time-release and dose-controllable manner

Addissouky TA, Ali M, Sayed ETE, Wang I

Acyl-CoA thioesterase 7 is involved in cell cycle progression via regulation of PKC-p53-p21 signaling pathway