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As depicted in our functional co-expression network ( Figure 8 ), hub TFs are tightly linked to downstream structural genes highly associated with these physiological responses

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However, the role of GPX3 related redox metabolism, especially its association with mitochondria on cell proliferation and cell death in BPH has not been well illustrated

The details of the multistep mechanism postulated for the reaction and the structural motifs of the several enzymes, which have been thoroughly investigated, cannot be described in detail