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GSTU20 has been assayed for activity toward model xenobiotic substrate CDNB and BITC which are the typical GST substrates, revealing high GSH-conjugating activity ( in vitro due to the rare abundance

In macrophages, HO-1 mediates both classical ferroptosis pathways via glutathione peroxidase 4 (GPX4) regulation and non-classical, erythrophagocytosis-induced ferroptosis, contributing to plaque instability

Evins, A

Additionally, we reviewed relevant research on the modulation of ferroptosis signaling pathways as a potential approach for developing antidepressant interventions