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We identified numerous somatic mutations that either increase or decrease berberine binding across multiple genes (Fig

and activation of NOX4 to generate lumenal H 2 O 2 , which would in contrast favor oxidation in the lumen by supplying H 2 O 2 for PRDX4 and GPx7/8

Production of pyocyanin in P

Reduction in wound healing time and rate of recurrence of chronic venous leg ulcers were described in two randomized double-blinded studies [1.3 ms pulse