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The reason is that it serves as a co-substrate in all reactions catalyzed by aminotransferases being converted to -ketoglutarate, a key intermediate in the TCA cycle (McKenna et al

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[DOI] [PMC free article] [PubMed] [Google Scholar] 26.Wang R., Li B., Huang B., Li Y., Liu Q., Lyu Z., Chen R., Qian Q., Liang X., Pu X., et al