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5.2 Mineralocorticoids hormone imbalance-associated oxidative stress According to numerous clinical and investigations in animal models, the most significant physiological mineralocorticoid, aldosterone, causes OS and inflammation in patients with chronic and stable heart failure (67)

bmj , 380

NcRNAs, including miRNAs [30], long noncoding RNAs (lncRNAs) [31], and circular noncoding RNAs (cncRNAs) [32], have been discovered as glutaminolysis regulators, and they may interact with oncogenes and tumor suppressors genes and influence the metabolism of cancer