glutathione fe3+ ncbi peroxidase gsh-px on iron Lipid Peroxidation and Metabolism: Two Corner Stones in the Homeostasis Control of Ferroptosis Glutathione Ferroptosis regulation in lysosome Lysosomal
Ferroptosis regulation in lysosome Lysosomal iron and cathepsin B contribute to ferroptotic cell death. Lysosomal cyst(e)ine can be mobilized to maintain glutathione synthesis and glutathione peroxidase 4 activity, thereby limiting lipid peroxidation. The mechanism of ferroptosis and its related diseases PMC Molecular Medicine Reports Computational discovery of novel GPX4 inhibitors from herbal sources as potential ferroptosis inducers in cancer therapy ScienceDirect
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