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Passive Smoking Passive smoking occurs when non-smokers, including babies and children, inhale the smoke released by cigarettes smoked by others
This was followed by 3 focus groups (range 48 participants), and an individual interview with 1 participant who could not attend the focus groups, to understand participants rationales for their ratings and factors that influenced their perception of importance of outcomes (Appendix 3)
Potential Biologic Mechanisms for the Association of Smoking with Increased Risk of SLE [Figure 2] There are many models of how environmental exposures may putatively contribute to SLE pathogenesis, among them, oxidative stress involving intracellular organelles such as mitochondria and endoplasmic reticulum [5052], elevated cytokine-driven systemic inflammation accelerating autoimmune disease onset [5355], and impaired T- and B-cell function [5660]
