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---------- Triamterene and hydrochlorothiazide combines triamterene, a potassium-conserving diuretic, with the natriuretic agent, hydrochlorothiazide

10.5812/ijpr-127035 19 FatahiY.SanjabiM.RakhshaniA.MotasadizadehH.DarbasizadehB.BahadorikhaliliS.et al (2021)

For a compound to gain FDA approval, it must go through extensive, multi-phase clinical trials in humans to prove both safety and efficacy for a specific condition