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doi: 10.1016/j.heliyon.2022.e09359 25 HannaL.-A.RaineyJ.HallM

Nausea represents the most commonly reported side effect in clinical trials

A Balanced Act of Mitochondrial Biogenesis and Mitophagy Mitochondrial function is multifaceted in response to cellular energy homeostasis and metabolism, including calcium homeostasis, amino acid metabolism, pyridine synthesis, cellular replication, apoptosis, reactive oxygen species (ROS) production, and senescence (Spinelli and Haigis, 2018)

The information below is drawn from individual-compound research and community reports, separated into compound-level effects and stack-specific concerns