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Furthermore, Fer-1 mitigates oxidative stress by downregulating prostaglandin endoperoxide synthase 2 while upregulating GPX4 and Nrf2, thereby decreasing lipid peroxidation (115)

Shoaib, M., Khaliq, H

Pregnancy and lactation represent relative contraindications given absence of human safety data in these populations despite reassuring preclinical reproductive toxicology studies