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Distant tumor metastasis to the lung changes staging, clinical prognosis and treatment options of the original tumor and severely decreases survival rate [3,4,5]

[DOI] [Google Scholar] 127.Cho K.S., Shin M., Kim S., Lee S.B

CD44 is involved in the regulation of diverse vital signaling pathways that modulate cancer proliferation, invasion, metastasis and therapy-resistance, and it is also modulated by a variety of molecules in cancer cells