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Proceedings of the National Academy of Sciences of the United States of America, 120 (15)

Calcium is transported into mitochondria to facilitate intracytoplasmic calcium removal and to stimulate metabolic processes, including ATP synthesis, ROS production, and apoptosis (Rosencrans et al., 2021

Our findings reveal that treatment with FGF21 enhances the import and concentration of mitochondrial GSH without affecting the overall levels of GSH in the cell