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Two types of basement membranes are present at the BBB, one secreted by pericytes and ECs, namely the vascular basement membrane, also called endothelial basement membrane, and the other formed by astrocytes, referred to as the glial basement membrane (also known as parenchymal basement membrane) [35, 36]

To further investigate the interaction between SMC and fresh UPR, an ozone treatment was carried out on SMC before blending and all the composites compared with no-treated reference systems

Macrophage fumarate hydratase restrains mtRNA-mediated interferon production

However, like many polymeric carriers, their intrinsic ability to cross the BBB is limited without functional modification