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Known postbiotics include intentionally inactivated microbial cells, bacterial lysates, extracellular polysaccharides, extracellular vesicles, surface proteins, metabolites, carbohydrates, enzymes, proteins, organic acids, lipids, vitamins, and complex molecules (Gowacka et al., 2024)

Kraft found that the expression of GCH1 triggered the production of potent antioxidant BH4, thus preventing lipid peroxidation [44]

FDA's Official Reasons: Lack of Clinical Trials: The FDA emphasizes the need for extensive, controlled clinical trials, which are currently lacking

It further induces oxidative stress by increasing generating ROS production