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Front Oncol 13:1257767 Avancini A, Borsati A, Toniolo L, Ciurnelli C, Belluomini L, Budolfsen T et al (2025) Physical activity guidelines in oncology: a systematic review of the current recommendations

Unlike normal cells, which rely primarily on oxidative phosphorylation or glycolysis, glioblastoma cells adapt to metabolic stress by shifting between these pathways to maintain energy production and cellular integrity [156, 157]

It neutralizes free radicals and protects healthy cells from damage

13 Moreover, most of the flavonoids, upon digestion, reach the colon unabsorbed and thus increase the abun- dance of beneficial bacteria and the production of short- chain fatty acids (FAs)