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Lowes et al., 2009

Potential therapeutic drugs The multifactorial nature of AD onset, coupled with the complex interactions among these factors, poses significant challenges to drug development

Folate (B9): Folate is essential for methylation and neurotransmitter synthesis, and low levels have been associated with increased risk of anxiety and depression, particularly in pregnant or postpartum women

Behav Brain Res 291:306314 Zhang Y, Xu S, Qian Y et al (2022) Sodium butyrate attenuates rotenone-induced toxicity by activation of autophagy through epigenetically regulating PGC-1 expression in PC12 cells