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On the other hand, some of the ferroptosis mechanisms themselves are unclear, and some of the mechanisms have been proposed but are still unknown (e.g., GCH1-BH4 pathway, HSF1-HSPB1 pathway, sulfur-transfer pathway, MVA pathway, etc.), which has become an important obstacle in the development of small molecule drugs

Nrf2, a CapnCollar transcription factor, regulates induction of the heme oxygenase-1 gene

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J., Shin, J