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After the enzymatic treatment, tissue pieces were washed three times with plating medium (Neurobasal medium containing 5% fetal bovine serum (Gibco 10437028), 1 B27 (Gibco 17504044), 1 Glutamax (Gibco 35050061)) and then dissociated by trituration in 2 ml of plating medium

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67.6% women) who were randomly assigned to receive subcutaneous cagrilintide/semaglutide (CagriSema, Novo Nordisk), semaglutide 2.4 mg alone (Wegovy, Novo Nordisk), cagrilintide 2.4 mg alone or placebo