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The FDA removed both from compounding availability in 2024

129 In a small pilot trial that enrolled 10 women with PCOS and randomized them to receive 200 mcg chromium picolinate or placebo daily for four months, chromium supplementation improved glucose tolerance but did not improve ovulatory frequency

The human body cannot produce B12, so it must be obtained through dietary sourcesprimarily animal products such as meat, fish, dairy, and eggsor through supplementation