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These results suggest that lesion activity and axonal damage in active MS lesions are likely to be caused by Glu excitotoxicity (82)

Also, prolonged NSW ( 10 years) correlated with hypomethylation in NR1D1, and hypermethylation of CSNK1E, a kinase regulating PER proteins downstream of CLOCK 215

This review begins by examining the landscape of cytokine delivery, emphasizing how it can be accomplished using nanoparticle systems encapsulating proteins, DNA or mRNA payloads