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J Biol Chem 284(11):7114-25, 2009

The paradigm of systemic therapy has shifted from traditional methods to subtype-specific and personalized approaches (Fig

Fluorescence imaging clearly showed the internalization of CuSAE after 1.5 h of incubation, with continuous accumulation reaching higher fluorescence intensity after 5 h, and remained in the cells for up to 12 h

Several metrics were meticulously recorded, including IBA-1 volume (in cubic micrometres), LAMP-1 volume within IBA-1, the number of synaptic terminal spots in LAMP-1, branching points, and the soma size of microglia (in cubic micrometres)