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Specifically, BPC 157 inhibited the mRNA of inflammatory mediators (iNOS, IL-6, IFN, and TNF-), increased the expression of HSP 70 and 90, and antioxidant proteins (such as HO-1, NQO-1, glutathione reductase, glutathione peroxidase 2, and GST-pi) ( Further, we should appreciate the noted methodology point (i.e., the vascular failure obtained by retrobulbar L-NAME injection and by therapy counteracted, as specific major findings, and the normal intraocular pressurethe severe eye damage)

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Release 72, 101113.10.1016/S0168-3659(01)00266-8 Summary Keywords angiogenesis, controlled release, biomaterials, drug delivery, hydrogels, depot-based, review Citation Van Hove AH and Benoit DSW (2015) Depot-Based Delivery Systems for Pro-Angiogenic Peptides: A Review