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By using machine learning algorithms, we analyzed the 15 genes with LASSO logistic regression and SVM-RFE analysis, and five hub genes were identified to be significantly associated with ferroptosis, such as HIF1A , ACSL1 , CD82 , PEX2 and TFAP2A

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that AFB1, as the parent compound, inhibited rat liver mitochondrial electron transport at the antimycin A-sensitive site (10) and postulated subsequently (5) that the enhanced liver cell necrosis and acute toxicity observed in the low-protein animals could be due to the low rate of metabolism and clearance of AFB1 with a consequent effect on mitochondrial respiration

What's more, creatine increases intracellular fluid, which can make muscles appear fuller