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Figure 5) was one of the first such compounds developed (Parnham and Sies, 2013)

These could be working as main intervention, or by partnering with other current pharmacological approaches

This heightened stress response reduces insulins effectiveness, pushing the body toward insulin resistance

DMSO reduced not only soluble but also insoluble mtHTT (mutant huntingtin aggregates) expressions, which were masked in the presence of autophagy inhibitor