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Horowitz MB, Pang D

J Neurochem 91:667682 de Haan JB, Bladier C, Griffiths P, Kelner M, OShea RD, Cheung NS, Bronson RT, Silvestro MJ, Wild S, Zheng SS, Beart PM, Hertzog PJ, Kola I (1998) Mice with a homozygous null mutation for the most abundant glutathione peroxidase, Gpx1, show increased susceptibility to the oxidative stress-inducing agents paraquat and hydrogen peroxide

The frequency of fibromyalgia increases significantly where patients have one of several chronic diseases, such as inflammatory or degenerative arthritis, chronic heart failure, chronic liver or kidney disease, among others

In the new era of molecular medicine, new proteomics methodologies promise to establish a relationship between pathological hallmarks of disease and protein structural and functional abnormalities in liver disease, thus allowing a better understanding and a more rational therapy on these disorders