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524 A substantial body of literature has demonstrated the potential of microbiome-based therapeutics in alleviating dopaminergic damage and motor deficits in PD mouse models

Thirty patients were prospectively enrolled at the Spinal Surgery Department and included 20 patients with LDH, suffering from radicular leg pain for less than 3 months and 10 patients with scoliosis or lumbar burst fracture as the control without leg painful symptomatology or degenerative disc disease