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Another annuloplasty method is the intradiscal biacuplasty, which involves placing two radiofrequency electrodes on the posterolateral sides of the annulus fibrosus (Kapural and Mekhail, 2007)

Similarly, olfactory have been found to improve peripheral nerve regeneration but unlike other sources, displays unique neurogenic characteristic that might make it ideally suited for cellular therapy 52

TIMP2 was found to be expressed by microglia (Skuljec et al., 2011), whereas the source of TIMP1 in the CNS is linked to astrocytes (Gardner and Ghorpade, 2003)

We will discuss the interaction between the gut-organ axes and intestinal barrier damage, further elucidate the signaling pathways underlying intestinal barrier damage, and summarize alterations in various components of the intestinal barrier under microgravity