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When applied topically or through injections, GHK-Cu penetrates the skin barrier to stimulate collagen production , enhance skin renewa l, and promote glycosaminoglycan production, such as hyaluronic acid

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Certain symptoms require escalation , including severe or worsening pain, progressive weakness, or changes in bowel or bladder function

The molecular mechanism of this neuroprotective activity involves regulation of B-cell lymphoma/leukaemia 2 (BCL2) family proteins and protein kinase-dependent signalling pathways as well as interactions with glyceraldehyde-3-phosphate dehydrogenase and induction of some antioxidant enzymes